September 2025 Cumulative Update not working with 24H2?

tired-it

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I am curious to know if anyone is having any similar issues because I cannot seem to figure out if NTLite might be having problems, the files themselves are problematic, or perhaps this is a Microsoft issue?

I have a untouched Windows 11 24H2 ISO downloaded straight from Microsoft's website. I load it into NTLite and apply the following 5 recommended updates:
  1. KB5068221 - Cumulative Update (Requirement KB5043080) - September Cumulative Update (26100.6588.1.0)
    1. KB5043080 - Cumulative Update (Checkpoint) - Preinstalled in the ISO by Microsoft (21600.1742.1.10)
  2. KB5064401 - .NET Framework 3.5/4.8.1 Cumulative Update (10.0.9316.1)
  3. Microsoft.UI.Xaml v2.8 (8.2501.3100.0)
  4. Microsoft Visual C++ UWP Runtime v14.00 (14.0.33728.0)
  5. KB5066990 - Dynamic Update for Windows Setup (10.0.26100.6580)
NTLite version 2025.8.10552

Update #1 brings up an error, "unreadable or unsupported file," even after the program successfully verifies the file. This is a huge file by the way, coming in at just over 3300MB (what gives Microsoft?). I have re-downloaded it multiple times. Other times the error message does not come up and the file seemingly works.

When it comes to integrating the update, NTLite seems to have a common enough error rate where I am wondering what going on. At least 2/3rds of the time, the updates integrate into the ISO with no issue. Otherwise, I receive an error mid-application that something went wrong with the update and it halts, forcing me to unmount and delete the whole project file. Any ideas as to what is causing this to occur?

Small side note, but are there any other updates worth applying to the image to further streamline the setup process of a new PC?
 
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Do you have an antivirus running in the background (just in case) ?
I haven't encountered any problems integrating updates (I download them directly from the MS catalog), and I don't count the number of tests

For the size of the CUs, for several months, MS has integrated the "MSIX" files for the Recall apps, etc... For the Copilot+ machines (NPU PC)
 
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Do you have an antivirus running in the background (just in case) ?
I haven't encountered any problems integrating updates (I download them directly from the MS catalog), and I don't count the number of tests

For the size of the CUs, for several months, MS has integrated the "MSIX" files for the Recall apps, etc... For the Copilot+ machines (NPU PC)
I have Defender's real-time protection turned off at all times while using NTLite.

And that about sounds right for those CUs. I get why MS does it, but geez does it suck to download a 3GB file as an update. They used to be so much smaller.
 
Ok, not antivirus then

Yes, it's clear, I remove the MSIX files from the .msu file, it takes up less "space"
 
Ok, not antivirus then

Yes, it's clear, I remove the MSIX files from the .msu file, it takes up less "space"
How do you remove the MSIX files from the .msu? I can view the file in 7zip and see loads of MSIX and msix.rif.cab files. Which ones would be safe to remove/keep? What is the final size of your .msu file after all the removals?
 
Looks like that trick brought the update file from 3.30 GB to 1.29GB. Oddly enough, the ISO size without ESD compression went from 6.31GB to 6.36GB. Make it make sense lol. I'm so tired so these inconsistencies.
 
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